| Patient ID | Age (y) | Sex | Confirmation of diagnosis | Treatment | Confirmation of recurrence | Confirmation of response to PBC | OS | PFS | |||||
| Pathology | Radiology | ||||||||||||
| Place and date | Diagnosis | Place and date | Diagnosis | Place and date | Assessment | Place and date | Assessment | ||||||
| 4 | 53 | M | University Hospital November 9, 2011 | Oligoastrocytoma, Grade 3, Gliomatosis | Regional Hospital October 21, 2011 MRI | Tumor (8 × 5.5 cm) of right temporal, occipital, parietal lobes and corpus callosum | University Hospital November 2011 Excisional biopsy | ||||||
| University Hospital November 21, 2011 | GBM | University Hospital November 14, 2011 Subtotal resection December 12, 2011-January 24, 2012 RT × 30 treatments | University Hospital January 8, 2012 MRI | No Recurrence | |||||||||
| TMZ 140 mg × 5 each week | Regional Radiology February 9, 2012 MRI | Recurrence | |||||||||||
| University Hospital February 27, 2012 | GBM | University Hospital February 25, 2012 Tumor resection | |||||||||||
| Regional Radiology April 19, 2012 Enhancing mass (5.2 × 4.3 cm) | Recurrence | ||||||||||||
| BC-April 18, 2012 PB, erlotinib, rapamycin, BVZ, TMZ, dexamethasone | |||||||||||||
| August 10, 2012 Discontinued dexamethasone. August 17, 2012 Discontinued BVZ. October 24, 2012 Discontinued TMZ. October 3, 2013 Discontinued erlotinib and rapamycin. March 7, 2014 Decreased PB by 30%. June 23, 2014 Discontinued PB | Regional Radiology May 29, 2012 to June 5, 2014 MRI. January 30, 2013 to August 16, 2013 PET | CR | 26 months | 26 months | |||||||||
| 5 | 57 | M | Regional Hospital September 2011 | AA | Regional Hospital July 20, 2011 CT | Frontotemporal mass (4 × 3.7 cm) | Regional Hospital September 15, 2011 Total tumor resection | ||||||
| Regional Radiology August 29, 2012 MRI | Recurrence | ||||||||||||
| Regional Hospital October 26, 2012 | GBM | Regional Hospital October 25, 2012 Total Tumor resection | |||||||||||